Protein Modification Reagents
Medchemexpress LLC Ald-Ph-amido-PEG4-C2-NHS ester | 1353011-74-1 | 98.1% | 494.49 g/mol | C23H30N2O10 | 100 MG
Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit polyethylene glycol (PEG) linker functionalized as an N-hydroxysuccinimide (NHS) ester for amine-reactive bioconjugation in antibody-drug conjugate (ADC) development. It is supplied for research use and is typically stored at low temperature.
- Non-cleavable 4-unit PEG linker for stable conjugation.
- NHS ester functional group for amine-reactive coupling.
- Molecular weight 494.49 g/mol.
- Molecular formula C23H30N2O10.
- CAS number 1353011-74-1.
- High purity (≈98.1%) suitable for research applications.
- Available in multiple package sizes from 50 mg to 10 g.
Medchemexpress LLC Ald-ph-amido-peg4-c2-acid | 1309460-27-2 | 99.1% | 397.42 | C19H27NO8 | 250 MG
Ald-Ph-amido-PEG4-C2-acid is a noncleavable polyethylene glycol (PEG4) linker intended for use in antibody-drug conjugate (ADC) research. It provides a stable, non-cleavable connection between an antibody and a payload, and is supplied at high purity to support reproducible bioconjugation.
- Noncleavable PEG4 linker suitable for ADC development.
- Terminal carboxylic acid enables amide coupling to payloads.
- Benzaldehyde moiety enables selective conjugation to hydrazide or aminooxy groups.
- High purity supports reproducible conjugation results.
- Molecular weight 397.42 g/mol and formula C19H27NO8.
Mitegen PEG 6000, 50%(w/v), 250 ml, CAS# 25322-68-3
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
Mitegen PEG 5000 MME, 50%(w/v), 250 ml, CAS# 9004-74-4
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
Mitegen PEG 1000, 50%(w/v), 250 ml, CAS# 25322-68-3
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
Mitegen PEG 300, 100%(v/v), 100 ml, CAS# 25322-68-3
Use our stock solutions directly or as a component in solutions you create in your own lab. We prepare our stock solutions using high quality raw materials, ASTM Type 1 water, and sterile packaging. Our stock solutions are intended for Research and Development Use Only.
Medchemexpress LLC TCO-PEG2-amine | 2141981-87-3 | ≥97.0% | C15H28N2O4 | 50 MG
TCO-PEG2-amine is a PEG-based PROTAC linker. This compound is used in the synthesis of PROTACs.
- Purity of ≥97.0%
- Molecular formula C15H28N2O4
- Molecular weight 300.39
- Appears as a colorless to light yellow liquid
- Recommended storage at 4°C, protected from light
- Suitable for PROTAC synthesis
Medchemexpress LLC Bromoacetamido-PEG4-acid | 1807518-67-7 | MFCD28950779 | 96.8% | 386.24 g·mol⁻¹ | C13H24BrNO7 | 500 MG
Bromoacetamido-PEG4-acid is a 4-unit polyethylene glycol (PEG4) linker bearing a bromoacetamido functional group. It is used as a cleavable spacer and reactive handle in the synthesis of PROTACs and antibody-drug conjugates (ADCs), providing aqueous solubility and sites for nucleophilic conjugation.
- 4-unit PEG spacer improves solubility and flexibility
- Bromoacetamido reactive group enables nucleophilic substitution conjugation
- Molecular weight 386.24 g·mol⁻¹
- CAS number 1807518-67-7
- Purity 96.8% (as supplied)
- Typical package size 500 MG
Medchemexpress LLC EGGGG-PEG8-amide-bis(deoxyglucitol) | 2842855-38-1 | 98.90% | C49H91N9O28 | 5 MG
EGGGG-PEG8-amide-bis(deoxyglucitol) is characterized as a cleavable ADC (Antibody-Drug Conjugate) linker. It appears as a solid-liquid mixture, white to off-white in color, with a molecular weight of 1254.29 and the chemical formula C49H91N9O28. This compound is intended for research use only.
- Cleavable ADC linker: functions as a component in antibody-drug conjugates, facilitating the release of a therapeutic payload at the target site.
- Appearance: presented as a white to off-white solid-liquid mixture.
- Solubility: soluble in DMSO at a concentration of 75 mg/mL (59.79 mM) with the aid of ultrasonication and warming to 60°C.
- Storage conditions: solid form: store at -20°C, protected from light. In solvent (stock solution): stable for 6 months at -80°C and 1 month at -20°C, protected from light.
Medchemexpress LLC N3-PEG3-CH2CH2COOH | 1056024-94-2 | ≥98.0% | 247.25 g/mol | C9H17N3O5 | 250 MG
N3-PEG3-CH2CH2COOH is an azido-terminated, triethylene glycol (PEG3) propionic acid linker reagent used in chemical synthesis for conjugation and click chemistry applications. It provides an azide functional group suitable for copper-catalyzed and strain-promoted azide-alkyne cycloadditions, and a carboxylic acid handle for covalent coupling.
- Azide functional group for CuAAC and SPAAC reactions.
- Triethylene glycol spacer for increased solubility and flexibility.
- Carboxylic acid handle for straightforward conjugation chemistry.
- High purity for research use.
- Stable under recommended storage: -20°C, protect from light; in solvent -80°C for up to 6 months.
Medchemexpress LLC Amino-PEG4-CH2COOH | 195071-49-9 | >=98.0% | 251.28 g/mol | C10H21NO6 | 100 MG
Amino-PEG4-CH2COOH is a PEG-based bifunctional linker supplied as a purified solid for use in synthetic chemistry. It provides an amino terminus and a terminal carboxylic acid for conjugation and spacer functionality in bifunctional molecules such as PROTACs and antibody-drug conjugates.
- Bifunctional linker with amino and carboxylic acid termini.
- Four-unit polyethylene glycol (PEG4) spacer for flexible linkage.
- High purity suitable for synthesis and research use.
- Low molecular weight and defined formula for analytical consistency.
- Available in small-scale research quantities for lab-scale synthesis.
Medchemexpress LLC Mal-PEG4-NHS ester | 1325208-25-0 | 99.4% | 442.42 | C19H26N2O10 | 250 MG
Mal-PEG4-NHS ester is a PEG-based crosslinker containing a maleimide group and an N-hydroxysuccinimide (NHS) ester separated by a four-unit polyethylene glycol spacer. It is used for conjugation of thiol-containing molecules to primary amines for bioconjugation and nanoparticle functionalization in research applications.
- Non-cleavable maleimide-NHS linker for thiol-to-amine conjugation.
- Four-unit polyethylene glycol spacer increases solubility.
- High purity (99.4% by HPLC).
- Molecular weight 442.42, formula C19H26N2O10.
- Available in small lab pack sizes, including 250 MG.
- For research use only; not for therapeutic use.
Medchemexpress LLC Bis-PEG4-NHS ester | 1g
Bis- PEG4- NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC)
Medchemexpress LLC Dopamine-PEG-N3 MW 10mg
Dopamine-PEG-N3 (MW 2000) (Dopamine-PEG-Azide (MW 2000)) is a compound composed of dopamine PEG segments and an azide group (-N3) Dopamine-PEG-N3 (MW 2000) can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials Dopamine-PEG-N3 (MW 2000) is a click chemistry reagent It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group
Medchemexpress LLC DBCO-PEG4-eosin 5-isothiocyanate | 96.7% | 1228.59 | C50H44Br4N4O11S | 10 MG
DBCO-PEG4-Eosin 5-isothiocyanate is a click-chemistry-enabled fluorescent probe that links a DBCO (dibenzocyclooctyne) reactive group to eosin 5-isothiocyanate via a PEG4 spacer. It is supplied as an orange-red solid for labeling biomolecules using strain-promoted alkyne-azide cycloaddition (SPAAC) and for fluorescence imaging applications.
- Enables copper-free click conjugation via DBCO
- PEG4 spacer improves solubility and reduces steric hindrance
- Eosin 5-isothiocyanate offers red-orange fluorescence for imaging
- High purity suitable for bioconjugation applications
- Supplied in small milligram quantities for research use
- Store sealed, protected from moisture and light; refrigerate for solids